RIM1/2-Mediated Facilitation of Cav1.4 Channel Opening Is Required for Ca(2+)-Stimulated Release in Mouse Rod Photoreceptors

Night blindness can result from impaired photoreceptor function and a subset of cases have been linked to dysfunction of Cav1.4 calcium channels and in turn compromised synaptic transmission. Here, we show that active zone proteins RIM1/2 are important regulators of Cav1.4 channel function in mouse...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Grabner, Chad P., Gandini, Maria A., Rehak, Renata, Le, Yun, Zamponi, Gerald W., Schmitz, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605434/
https://ncbi.nlm.nih.gov/pubmed/26400943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0658-15.2015
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