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CPProtectides: Rapid uptake of well-folded β-hairpin peptides with enhanced resistance to intracellular degradation

Cell penetrating peptides (CPPs) have emerged as powerful tools for delivering bioactive cargoes, such as biosensors or drugs to intact cells. One limitation of CPPs is their rapid degradation by intracellular proteases. β-hairpin “protectides” have previously been demonstrated to be long-lived unde...

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Bibliographic Details
Published in:Pept Sci (Hoboken)
Main Authors: Safa, Nora, Anderson, Jeffery C., Vaithiyanathan, Manibarathi, Pettigrew, Jacob H., Pappas, Gavin A., Liu, Dong, Gauthier, Ted J., Melvin, Adam T.
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605100/
https://ncbi.nlm.nih.gov/pubmed/31276085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pep2.24092
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