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Evaluating accessibility of intravenously administered nanoparticles at the lesion site in rat and pig contusion models of spinal cord injury

In spinal cord injury (SCI), timely therapeutic intervention is critical to inhibit the post-injury rapidly progressing degeneration of spinal cord. Towards that objective, we determined the accessibility of intravenously administered biodegradable nanoparticles (NPs) as a drug delivery system to th...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Gao, Yue, Vijayaraghavalu, Sivakumar, Stees, Melinda, Kwon, Brian K., Labhasetwar, Vinod
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605058/
https://ncbi.nlm.nih.gov/pubmed/30930216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2019.03.026
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