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The role of HIF-1α in the TGF-β2-mediated epithelial-to-mesenchymal transition of human lens epithelial cells

Human lens epithelial cells (HLE) undergo mesenchymal transition and become fibrotic during posterior capsule opacification (PCO), which is a frequent complication after cataract surgery. TGF-β2 has been implicated in this fibrosis. Previous studies have focused on the role of hypoxia-inducible fact...

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Vydáno v:J Cell Biochem
Hlavní autoři: Nahomi, Rooban B., Nagaraj, Ram H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605039/
https://ncbi.nlm.nih.gov/pubmed/29693273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.26877
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