Simvastatin Reduces Hepatic Oxidative Stress and Endoplasmic Reticulum Stress in Nonalcoholic Steatohepatitis Experimental Model

OBJECTIVE: In this study, we evaluated the efficacy of simvastatin in the treatment of nonalcoholic steatohepatitis induced by methionine and choline-deficient diet in mice and its possible effect on factors involved in the pathogenesis of the disease including oxidative stress and endoplasmic retic...

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Bibliografiske detaljer
Udgivet i:Oxid Med Cell Longev
Main Authors: Rodrigues, Graziella, Moreira, Andrea Janz, Bona, Silvia, Schemitt, Elizângela, Marroni, Cláudio Augusto, Di Naso, Fábio Cangeri, Dias, Alexandre Simões, Pires, Thienne Rocha, Picada, Jaqueline Nascimento, Marroni, Norma Possa
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604429/
https://ncbi.nlm.nih.gov/pubmed/31316716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/3201873
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