Cardiac ischemia–reperfusion injury under insulin-resistant conditions: SGLT1 but not SGLT2 plays a compensatory protective role in diet-induced obesity

BACKGROUND: Recent large-scale clinical trials have shown that SGLT2-inhibitors reduce cardiovascular events in diabetic patients. However, the regulation and functional role of cardiac sodium–glucose cotransporter (SGLT1 is the dominant isoform) compared with those of other glucose transporters (in...

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Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cardiovasc Diabetol
Hauptverfasser: Yoshii, Akira, Nagoshi, Tomohisa, Kashiwagi, Yusuke, Kimura, Haruka, Tanaka, Yoshiro, Oi, Yuhei, Ito, Keiichi, Yoshino, Takuya, Tanaka, Toshikazu D., Yoshimura, Michihiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Original Investigation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604374/
https://ncbi.nlm.nih.gov/pubmed/31262297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-019-0889-y
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