Chemotherapeutic Stress Induces Transdifferentiation of Glioblastoma Cells to Endothelial Cells and Promotes Vascular Mimicry

Glioblastoma (GBM) is the most common and aggressive primary malignant brain tumor affecting adults, with a median survival of approximately 21 months. One key factor underlying the limited efficacy of current treatment modalities is the remarkable plasticity exhibited by GBM cells, which allows the...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Baisiwala, Shivani, Auffinger, Brenda, Caragher, Seamus P., Shireman, Jack M., Ahsan, Riasat, Lee, Gina, Hasan, Tanwir, Park, Cheol, Saathoff, Miranda R., Christensen, Anne C., Ahmed, Atique U.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604352/
https://ncbi.nlm.nih.gov/pubmed/31316566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/6107456
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