Polled Digital Cell Sorter (p-DCS): Automatic identification of hematological cell types from single cell RNA-sequencing clusters

BACKGROUND: Single cell RNA sequencing (scRNA-seq) brings unprecedented opportunities for mapping the heterogeneity of complex cellular environments such as bone marrow, and provides insight into many cellular processes. Single cell RNA-seq has a far larger fraction of missing data reported as zeros...

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Detalles Bibliográficos
Publicado en:BMC Bioinformatics
Main Authors: Domanskyi, Sergii, Szedlak, Anthony, Hawkins, Nathaniel T, Wang, Jiayin, Paternostro, Giovanni, Piermarocchi, Carlo
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
Assuntos:
Methodology Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604348/
https://ncbi.nlm.nih.gov/pubmed/31262249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2951-x
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