Oscillatory Shear Stress Induces Oxidative Stress via TLR4 Activation in Endothelial Cells

BACKGROUND: Oscillatory shear stress (OSS) disrupts endothelial homeostasis and promotes oxidative stress, which can lead to atherosclerosis. In atherosclerotic lesions, Toll-like receptor 4 (TLR4) is highly expressed. However, the molecular mechanism by which TLR4 modulates oxidative changes and th...

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Sparad:
Bibliografiska uppgifter
I publikationen:Mediators Inflamm
Huvudupphovsmän: Wang, Zhimei, Wang, Feng, Kong, Xiangquan, Gao, Xiaofei, Gu, Yue, Zhang, Junjie
Materialtyp: Artigo
Språk:Inglês
Publicerad: Hindawi 2019
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604343/
https://ncbi.nlm.nih.gov/pubmed/31316302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/7162976
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