Plasmacytoid dendritic cells orchestrate innate and adaptive anti-tumor immunity induced by oncolytic coxsackievirus A21

BACKGROUND: The oncolytic virus, coxsackievirus A21 (CVA21), has shown promise as a single agent in several clinical trials and is now being tested in combination with immune checkpoint blockade. Combination therapies offer the best chance of disease control; however, the design of successful combin...

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Veröffentlicht in:J Immunother Cancer
Hauptverfasser: Müller, Louise M. E., Holmes, Matthew, Michael, Joanne L., Scott, Gina B., West, Emma J., Scott, Karen J., Parrish, Christopher, Hall, Kathryn, Stäble, Sina, Jennings, Victoria A., Cullen, Matthew, McConnell, Stewart, Langton, Catherine, Tidswell, Emma L., Shafren, Darren, Samson, Adel, Harrington, Kevin J., Pandha, Hardev, Ralph, Christy, Kelly, Richard J., Cook, Gordon, Melcher, Alan A., Errington-Mais, Fiona
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604201/
https://ncbi.nlm.nih.gov/pubmed/31262361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0632-y
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