Plasmacytoid dendritic cells orchestrate innate and adaptive anti-tumor immunity induced by oncolytic coxsackievirus A21

BACKGROUND: The oncolytic virus, coxsackievirus A21 (CVA21), has shown promise as a single agent in several clinical trials and is now being tested in combination with immune checkpoint blockade. Combination therapies offer the best chance of disease control; however, the design of successful combin...

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Gepubliceerd in:J Immunother Cancer
Hoofdauteurs: Müller, Louise M. E., Holmes, Matthew, Michael, Joanne L., Scott, Gina B., West, Emma J., Scott, Karen J., Parrish, Christopher, Hall, Kathryn, Stäble, Sina, Jennings, Victoria A., Cullen, Matthew, McConnell, Stewart, Langton, Catherine, Tidswell, Emma L., Shafren, Darren, Samson, Adel, Harrington, Kevin J., Pandha, Hardev, Ralph, Christy, Kelly, Richard J., Cook, Gordon, Melcher, Alan A., Errington-Mais, Fiona
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2019
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604201/
https://ncbi.nlm.nih.gov/pubmed/31262361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0632-y
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