Genetic Variants Associated With Corneal Biomechanical Properties and Potentially Conferring Susceptibility to Keratoconus in a Genome-Wide Association Study

IMPORTANCE: Keratoconus is an important cause of visual loss in young adults, but little is known about its genetic causes. Understanding the genetic determinants of corneal biomechanical factors may in turn teach us about keratoconus etiology. OBJECTIVES: To identify genetic associations with corne...

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Vydáno v:JAMA Ophthalmol
Hlavní autoři: Khawaja, Anthony P., Rojas Lopez, Karla E., Hardcastle, Alison J., Hammond, Chris J., Liskova, Petra, Davidson, Alice E., Gore, Daniel M., Hafford Tear, Nathan J., Pontikos, Nikolas, Hayat, Shabina, Wareham, Nick, Khaw, Kay-Tee, Tuft, Stephen J., Foster, Paul J., Hysi, Pirro G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Medical Association 2019
Témata:
Original Investigation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604088/
https://ncbi.nlm.nih.gov/pubmed/31246245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaophthalmol.2019.2058
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