Inhibition of LTA4H by bestatin in human and mouse colorectal cancer

BACKGROUND: Our preclinical data showed that the leukotriene A4 hydrolase (LTA4H) pathway plays a role in colorectal cancer (CRC). High expression of LTA4H and leukotriene B4 receptor type 1 (BLT1) were also associated with CRC survival probability. Clinical samples were evaluated to determine wheth...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Zhao, Simin, Yao, Ke, Li, Dan, Liu, Kangdong, Jin, Guoguo, Yan, Mingyang, Wu, Qiong, Chen, Hanyong, Shin, Seung Ho, Bai, Ruihua, Wang, Gangcheng, Bode, Ann M., Dong, Ziming, Guo, Zhiping, Dong, Zigang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604047/
https://ncbi.nlm.nih.gov/pubmed/31085102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.05.008
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