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Multiple myeloma clonal evolution in homogeneously treated patients

Clonal evolution drives tumor progression, chemoresistance and relapse in cancer. Little is known about clonal selection induced by therapeutic pressure in multiple myeloma. To address this issue, we performed large targeted sequencing of bone marrow plasma cells in 43 multiple myeloma patients at d...

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Bibliografiske detaljer
Udgivet i:Leukemia
Main Authors: Corre, Jill, Cleynen, Alice, du Pont, Sébastien Robiou, Buisson, Laure, Bolli, Niccolo, Attal, Michel, Munshi, Nikhil, Avet-Loiseau, Hervé
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6603429/
https://ncbi.nlm.nih.gov/pubmed/29895955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-018-0153-6
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