Endogenous Expression of the Human CD83 Attenuates EAE Symptoms in Humanized Transgenic Mice and Increases the Activity of Regulatory T Cells

The CD83 is a type I membrane protein and part of the immunoglobulin superfamily of receptors. CD83 is involved in the regulation of antigen presentation and dendritic cell dependent allogeneic T cell proliferation. A soluble form of CD83 inhibits dendritic cell maturation and function. Furthermore,...

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Publicado no:Front Immunol
Main Authors: Zinser, Elisabeth, Naumann, Ronald, Wild, Andreas B., Michalski, Julia, Deinzer, Andrea, Stich, Lena, Kuhnt, Christine, Steinkasserer, Alexander, Knippertz, Ilka
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6603205/
https://ncbi.nlm.nih.gov/pubmed/31293592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01442
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