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Residue Mutations in Murine Herpesvirus 68 Immunomodulatory Protein M3 Reveal Specific Modulation of Chemokine Binding

The M3 protein (M3) encoded by murine gammaherpesvirus 68 (MHV-68) is a unique viral immunomodulator with a high-affinity for a broad spectrum of chemokines, key mediators responsible for the migration of immune cells to sites of inflammation. M3 is currently being studied as a very attractive and d...

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Bibliografiske detaljer
Udgivet i:Front Cell Infect Microbiol
Main Authors: Šebová, Radka, Bauerová-Hlinková, Vladena, Beck, Konrad, Nemčovičová, Ivana, Bauer, Jacob, Kúdelová, Marcela
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6603146/
https://ncbi.nlm.nih.gov/pubmed/31293981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00210
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