Middle Ear Administration of a Particulate Chitosan Gel in an in vivo Model of Cisplatin Ototoxicity

BACKGROUND: Middle ear (intratympanic, IT) administration is a promising therapeutic method as it offers the possibility of achieving high inner ear drug concentrations with low systemic levels, thus minimizing the risk of systemic side effects and drug-drug interactions. Premature elimination throu...

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Bibliografische gegevens
Gepubliceerd in:Front Cell Neurosci
Hoofdauteurs: Videhult Pierre, Pernilla, Fransson, Anette, Kisiel, Marta Alina, Damberg, Peter, Nikkhou Aski, Sahar, Andersson, Mats, Hällgren, Lotta, Laurell, Göran
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2019
Onderwerpen:
Neuroscience
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6603134/
https://ncbi.nlm.nih.gov/pubmed/31293387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00268
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