Individual Vulnerability to Stress Is Associated With Increased Demand for Intravenous Heroin Self-administration in Rats

Opioid use is a widespread epidemic, and traumatic stress exposure is a critical risk factor in opioid use and relapse. There is a significant gap in our understanding of how stress contributes to heroin use, and there are limited studies investigating individual differences underlying stress reacti...

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Detalhes bibliográficos
Publicado no:Front Behav Neurosci
Main Authors: Stafford, Nathaniel P., Kazan, Theodore N., Donovan, Colleen M., Hart, Erin E., Drugan, Robert C., Charntikov, Sergios
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6603087/
https://ncbi.nlm.nih.gov/pubmed/31293400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2019.00134
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