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Major changes in chromosomal somy, gene expression and gene dosage driven by Sb(III) in Leishmania braziliensis and Leishmania panamensis

Leishmania braziliensis and Leishmania panamensis are two species clinically and epidemiologically important, among others because of their relative resistance to first-line drugs (antimonials). The precise mechanism underlying the ability of these species to survive antimony treatment remains unkno...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Patino, Luz H., Imamura, Hideo, Cruz-Saavedra, Lissa, Pavia, Paula, Muskus, Carlos, Méndez, Claudia, Dujardin, Jean Claude, Ramírez, Juan David
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6603004/
https://ncbi.nlm.nih.gov/pubmed/31263131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45538-9
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