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Activated T-Follicular Helper 2 Cells Are Associated With Disease Activity in IgG4-Related Sclerosing Cholangitis and Pancreatitis

Immunoglobulin G4-related sclerosing cholangitis (IgG4-SC) and autoimmune pancreatitis (AIP) are characterized by an abundance of circulating and tissue IgG4-positive plasma cells. T-follicular helper (Tfh) cells are necessary for B-cell differentiation into plasma cells. We aimed at elucidating the...

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Detalhes bibliográficos
Publicado no:Clin Transl Gastroenterol
Main Authors: Cargill, Tamsin, Makuch, Mateusz, Sadler, Ross, Lighaam, Laura C., Peters, Rory, van Ham, Marieke, Klenerman, Paul, Bateman, Adrian, Rispens, Theo, Barnes, Eleanor, Culver, Emma L.
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602789/
https://ncbi.nlm.nih.gov/pubmed/31033594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14309/ctg.0000000000000020
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