Effects of the Selective α5-GABAAR Antagonist S44819 on Excitability in the Human Brain: A TMS–EMG and TMS–EEG Phase I Study

Alpha-5 gamma-aminobutyric acid type A receptors (α5-GABAARs) are located extrasynaptically, regulate neuronal excitability through tonic inhibition, and are fundamentally important for processes such as plasticity and learning. For example, pharmacological blockade of α5-GABAAR in mice with ischemi...

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Vydáno v:J Neurosci
Hlavní autoři: Darmani, Ghazaleh, Zipser, Carl M., Böhmer, Gabriele M., Deschet, Karine, Müller-Dahlhaus, Florian, Belardinelli, Paolo, Schwab, Matthias, Ziemann, Ulf
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2016
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601976/
https://ncbi.nlm.nih.gov/pubmed/27927951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1689-16.2016
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