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The Role of Chromatin Accessibility in cis-Regulatory Evolution

Transcription factor (TF) binding is determined by sequence as well as chromatin accessibility. Although the role of accessibility in shaping TF-binding landscapes is well recorded, its role in evolutionary divergence of TF binding, which in turn can alter cis-regulatory activities, is not well unde...

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Detalhes bibliográficos
Publicado no:Genome Biol Evol
Main Authors: Peng, Pei-Chen, Khoueiry, Pierre, Girardot, Charles, Reddington, James P, Garfield, David A, Furlong, Eileen E M, Sinha, Saurabh
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601868/
https://ncbi.nlm.nih.gov/pubmed/31114856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evz103
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