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Tau Accumulation, Altered Phosphorylation, and Missorting Promote Neurodegeneration in Glaucoma

Glaucoma, the leading cause of irreversible blindness worldwide, is characterized by the selective death of retinal ganglion cells (RGCs). Ocular hypertension is the most significant known risk factor for developing the disease, but the mechanism by which elevated pressure damages RGCs is currently...

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Podrobná bibliografie
Vydáno v:J Neurosci
Hlavní autoři: Chiasseu, Marius, Cueva Vargas, Jorge L., Destroismaisons, Laurie, Vande Velde, Christine, Leclerc, Nicole, Di Polo, Adriana
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601840/
https://ncbi.nlm.nih.gov/pubmed/27225768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3986-15.2016
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