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Evolutionary tuning impacts the design of bacterial tRNAs for the incorporation of unnatural amino acids by ribosomes
In order to function on the ribosome with uniform rate and adequate accuracy, each bacterial tRNA has evolved to have a characteristic sequence and set of modifications that compensate for the differing physical properties of its esterified amino acid and its codon-anticodon interaction. The sequenc...
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| Udgivet i: | Curr Opin Chem Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6601615/ https://ncbi.nlm.nih.gov/pubmed/30059836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2018.07.016 |
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