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Redirected optimized cell killing (ROCK®): A highly versatile multispecific fit-for-purpose antibody platform for engaging innate immunity

Redirection of immune cells to efficiently eliminate tumor cells holds great promise. Natural killer cells (NK), macrophages, or T cells are specifically engaged with target cells expressing markers after infection or neoplastic transformation, resulting in their activation and subsequent killing of...

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Podrobná bibliografie
Vydáno v:MAbs
Hlavní autoři: Ellwanger, Kristina, Reusch, Uwe, Fucek, Ivica, Wingert, Susanne, Ross, Thorsten, Müller, Thomas, Schniegler-Mattox, Ute, Haneke, Torsten, Rajkovic, Erich, Koch, Joachim, Treder, Martin, Tesar, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601565/
https://ncbi.nlm.nih.gov/pubmed/31172847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1616506
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