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Clustered telomeres in phase-separated nuclear condensates engage mitotic DNA synthesis through BLM and RAD52
Alternative lengthening of telomeres (ALT) is a telomerase-independent telomere maintenance mechanism that occurs in a subset of cancers. One of the hallmarks of ALT cancer is the excessively clustered telomeres in promyelocytic leukemia (PML) bodies, represented as large bright telomere foci. Here,...
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| Vydáno v: | Genes Dev |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6601508/ https://ncbi.nlm.nih.gov/pubmed/31171703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.324905.119 |
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