SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18

SETD1A is a SET domain-containing methyltransferase involved in epigenetic regulation of transcription. It is the main catalytic component of a multiprotein complex that methylates lysine 4 of histone H3, a histone mark associated with gene activation. In humans, six related protein complexes with p...

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Publicat a:Mol Cell Proteomics
Autors principals: Alsulami, Manal, Munawar, Nayla, Dillon, Eugene, Oliviero, Giorgio, Wynne, Kieran, Alsolami, Mona, Moss, Catherine, Ó Gaora, Peadar, O'Meara, Fergal, Cotter, David, Cagney, Gerard
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601208/
https://ncbi.nlm.nih.gov/pubmed/31076518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA119.001518
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