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A Novel Assay for RNA Polymerase I Transcription Elongation Sheds Light on the Evolutionary Divergence of Eukaryotic RNA Polymerases

Eukaryotic cells express at least three nuclear RNA polymerases (Pols), each with a unique set of gene targets. Though these enzymes are homologous, there are many differences among the Pols. In this study, a novel assay for Pol I transcription elongation was developed to probe enzymatic differences...

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Vydáno v:Biochemistry
Hlavní autoři: Scull, Catherine E., Ingram, Zachariah M., Lucius, Aaron L., Schneider, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600827/
https://ncbi.nlm.nih.gov/pubmed/30912638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b01256
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