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One-Step Regioselective Synthesis of Benzofurans from Phenols and α-Haloketones

Reported here is the direct synthesis of naphthofurans and benzofurans from readily available phenols and α-haloketones promoted by titanium tetrachloride which combines Friedel–Crafts-like alkylation and intramolecular cyclodehydration into one step. This simple protocol allows for the formation of...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Wang, Bingqiao, Zhang, Qiu, Luo, Juan, Gan, Zongjie, Jiang, Wengao, Tang, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600630/
https://ncbi.nlm.nih.gov/pubmed/31212606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24112187
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