Design, Synthesis, and Bioactive Screen In Vitro of Cyclohexyl (E)-4-(Hydroxyimino)-4-Phenylbutanoates and Their Ethers for Anti-Hepatitis B Virus Agents

A series of oxime Cyclohexyl (E)-4-(hydroxyimino)-4-phenylbutanoates and their ethers were designed, synthesized, and evaluated for anti-hepatitis B virus (HBV) activities with HepG 2.2.15 cell line in vitro. Most of these compounds possessed anti-HBV activities, and among them, compound 4B-2 showed...

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Publicado en:Molecules
Main Authors: Cui, Xinhua, Zhou, Min, Tan, Jie, Wei, Zhuocai, Wei, Wanxing, Luo, Peng, Lin, Cuiwu
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600592/
https://ncbi.nlm.nih.gov/pubmed/31151219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24112063
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