Esculetin, a Coumarin Derivative, Prevents Thrombosis: Inhibitory Signaling on PLCγ2–PKC–AKT Activation in Human Platelets

Esculetin, a bioactive 6,7-dihydroxy derivative of coumarin, possesses pharmacological activities against obesity, diabetes, renal failure, and cardiovascular disorders (CVDs). Platelet activation plays a major role in CVDs. Thus, disrupting platelet activation represents an attractive therapeutic t...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Int J Mol Sci
Hlavní autoři: Hsia, Chih-Wei, Lin, Kao-Chang, Lee, Tzu-Yin, Hsia, Chih-Hsuan, Chou, Duen-Suey, Jayakumar, Thanasekaran, Velusamy, Marappan, Chang, Chao-Chien, Sheu, Joen-Rong
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600380/
https://ncbi.nlm.nih.gov/pubmed/31163690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20112731
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky