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Porcine Reproductive and Respiratory Syndrome Virus Nonstructural Protein 1 Beta Interacts with Nucleoporin 62 To Promote Viral Replication and Immune Evasion

Porcine reproductive and respiratory syndrome virus (PRRSV) blocks host mRNA nuclear export to the cytoplasm, and nonstructural protein 1 beta (nsp1β) of PRRSV has been identified as the protein that disintegrates the nuclear pore complex. In the present study, the molecular basis for the inhibition...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Ke, Hanzhong, Han, Mingyuan, Kim, Jineui, Gustin, Kurt E., Yoo, Dongwan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600190/
https://ncbi.nlm.nih.gov/pubmed/31043527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00469-19
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