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BK Polyomavirus Activates the DNA Damage Response To Prolong S Phase

BK polyomavirus (PyV) is a major source of kidney failure in transplant recipients. The standard treatment for patients with lytic BKPyV infection is to reduce immunosuppressive therapy, which increases the risk of graft rejection. PyVs are DNA viruses that rely upon host replication proteins for vi...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Justice, Joshua L., Needham, Jason M., Thompson, Sunnie R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600189/
https://ncbi.nlm.nih.gov/pubmed/31043526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00130-19
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