Exogenous Administration of Low-Dose Lipopolysaccharide Potentiates Liver Fibrosis in a Choline-Deficient l-Amino-Acid-Defined Diet-Induced Murine Steatohepatitis Model

Various rodent models have been proposed for basic research; however, the pathogenesis of human nonalcoholic steatohepatitis (NASH) is difficult to closely mimic. Lipopolysaccharide (LPS) has been reported to play a pivotal role in fibrosis development during NASH progression via activation of toll-...

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Udgivet i:Int J Mol Sci
Main Authors: Nakanishi, Keisuke, Kaji, Kosuke, Kitade, Mitsuteru, Kubo, Takuya, Furukawa, Masanori, Saikawa, Soichiro, Shimozato, Naotaka, Sato, Shinya, Seki, Kenichiro, Kawaratani, Hideto, Moriya, Kei, Namisaki, Tadashi, Yoshiji, Hitoshi
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600174/
https://ncbi.nlm.nih.gov/pubmed/31163617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20112724
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