Inhibition of host NOX1 blocks tumor growth and enhances checkpoint inhibitor–based immunotherapy

NADPH oxidases catalyze the production of reactive oxygen species and are involved in physio/pathological processes. NOX1 is highly expressed in colon cancer and promotes tumor growth. To investigate the efficacy of NOX1 inhibition as an anticancer strategy, tumors were grown in immunocompetent, imm...

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Bibliografische gegevens
Gepubliceerd in:Life Sci Alliance
Hoofdauteurs: Stalin, Jimmy, Garrido-Urbani, Sarah, Heitz, Freddy, Szyndralewiez, Cédric, Jemelin, Stephane, Coquoz, Oriana, Ruegg, Curzio, Imhof, Beat A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Life Science Alliance LLC 2019
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599972/
https://ncbi.nlm.nih.gov/pubmed/31249132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800265
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