PARP1 expression in soft tissue sarcomas is a poor‐prognosis factor and a new potential therapeutic target

Soft tissue sarcomas (STSs) are aggressive tumors with few efficient systemic therapies. Poly(ADP‐ribose) polymerase‐1 (PARP1) inhibitors represent an emerging therapeutic option in tumors with genomic instability. The genomics of STSs is complex in more than half of cases, suggesting a high level o...

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Bibliografiske detaljer
Udgivet i:Mol Oncol
Main Authors: Bertucci, François, Finetti, Pascal, Monneur, Audrey, Perrot, Delphine, Chevreau, Christine, Le Cesne, Axel, Blay, Jean‐Yves, Mir, Olivier, Birnbaum, Daniel
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599836/
https://ncbi.nlm.nih.gov/pubmed/31131495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12522
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