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Impact of metal oxide nanoparticles on in vitro DNA amplification

Polymerase chain reaction (PCR) is used as an in vitro model system of DNA replication to assess the genotoxicity of nanoparticles (NPs). Prior results showed that several types of NPs inhibited PCR efficiency and increased amplicon error frequency. In this study, we examined the effects of various...

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Publicat a:PeerJ
Autors principals: Gao, Chun-Hui, Mortimer, Monika, Zhang, Ming, Holden, Patricia A., Cai, Peng, Wu, Shan, Xin, Yuexing, Wu, Yichao, Huang, Qiaoyun
Format: Artigo
Idioma:Inglês
Publicat: PeerJ Inc. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599668/
https://ncbi.nlm.nih.gov/pubmed/31293839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.7228
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