Functionalization of SF/HAP Scaffold with GO-PEI-miRNA inhibitor Complexes to Enhance Bone Regeneration through Activating Transcription Factor 4

Evidence indicates that microRNAs (miRNAs) play vital roles in regulating osteogenic differentiation and bone formation. Methods: Here, we show that a polyethyleneimine (PEI)-functionalized graphene oxide (GO) complex efficiently loaded with the miR-214 inhibitor is assembled into silk fibroin/hydro...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Ou, Lingling, Lan, Yong, Feng, Zhiqiang, Feng, Longbao, Yang, Junjie, Liu, Yu, Bian, Liming, Tan, Jiali, Lai, Renfa, Guo, Rui
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599658/
https://ncbi.nlm.nih.gov/pubmed/31285777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.34676
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