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Total internal reflection-based single-vesicle in situ quantitative and stoichiometric analysis of tumor-derived exosomal microRNAs for diagnosis and treatment monitoring

Purpose: Exosomes (EXs) have been increasingly recognized as natural nanoscale vehicles for microRNA (miRNA)-based cell-cell communication and an ideal source of miRNA biomarkers in bodily fluids. Current methods allow bulk analysis of the miRNA contents of EXs, but these approaches are not suitable...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: He, Dinggeng, Wang, Huizhen, Ho, See-Lok, Chan, Hei-Nga, Hai, Luo, He, Xiaoxiao, Wang, Kemin, Li, Hung-Wing
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599656/
https://ncbi.nlm.nih.gov/pubmed/31285775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.33683
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