E-cadherin is down-regulated in benign prostate hyperplasia and required for tight junction formation and permeability barrier in prostatic epithelial cell monolayer

BACKGROUND: We previously reported the presence of prostate specific antigen (PSA) in the stromal compartment of benign prostate hyperplasia (BPH). Since PSA is expressed exclusively by prostatic luminal epithelial cells, PSA in the BPH stroma suggests increased tissue permeability and the compromis...

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Udgivet i:Prostate
Main Authors: Li, Feng, Pascal, Laura E., Stolz, Donna B., Wang, Ke, Zhou, Yibin, Chen, Wei, Xu, Yadong, Chen, Yule, Dhir, Rajiv, Parwani, Anil V., Nelson, Joel B., DeFranco, Donald B., Yoshimura, Naoki, Balasubramani, Goundappa K., Gingrich, Jeffrey R., Maranchie, Jodi K., Jacobs, Bruce L., Davies, Benjamin J., Hrebinko, Ronald L., Bigley, Joel D., McBride, Dawn, Guo, Peng, He, Dalin, Wang, Zhou
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599563/
https://ncbi.nlm.nih.gov/pubmed/31212363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.23806
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