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What are the difficulties in conducting randomised controlled trials of thromboprophylaxis in myeloma patients and how can we address these? Lessons from apixaban versus LMWH or aspirin as thromboprophylaxis in newly diagnosed multiple myeloma (TiMM) feasibility clinical trial

Routine thromboprophylaxis (TP) in newly-diagnosed multiple myeloma (NDMM) patients comprises either aspirin for standard risk patients or low molecular weight heparin for high risk patients. Studies using DOACs in cancer patients include few with myeloma. The aim of this feasibility clinical trial...

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Podrobná bibliografie
Vydáno v:J Thromb Thrombolysis
Hlavní autoři: Sayar, Zara, Czuprynska, Julia, Patel, Jignesh P., Benjamin, Reuben, Roberts, Lara N., Patel, Raj K., Cornelius, Victoria, Arya, Roopen
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599493/
https://ncbi.nlm.nih.gov/pubmed/31168688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11239-019-01891-0
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