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Confirmation of Ath26 locus on chromosome 17 and identification of Cyp4f13 as an atherosclerosis modifying gene

BACKGROUND AND AIMS: We previously demonstrated that Apoe(−/−) mice on the DBA/2 vs. the AKR genetic background have >10-fold larger atherosclerotic lesions. Prior quantitative trait locus mapping via strain intercrossing identified a region on chromosome 17, Ath26, as the strongest atheroscleros...

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Detalhes bibliográficos
Publicado no:Atherosclerosis
Main Authors: Han, Juying, Robinet, Peggy, Ritchey, Brian, Andro, Heather, Smith, Jonathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599485/
https://ncbi.nlm.nih.gov/pubmed/31102955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2019.05.007
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