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Gene mapping and molecular analysis of hereditarynon-polyposis colorectal cancer (Lynch Syndrome)using systems biological approaches

Hereditary non-polyposis colorectal cancer (HNPCC) also known as Lynch Syndrome (LS), is a hereditary form of colorectal cancer (CRC). LSis caused by mutations in the mismatch repair (MMR) genes, mostly in MLH1, MSH2, MSH6 and PMS2. Identification of these gene mutations is essential to diagnose CRC...

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Detalhes bibliográficos
Publicado no:Bioinformation
Main Authors: Rasool, Mahmood, Karim, Sajjad, Naseer, Muhammad Imran, Pushparaj, Peter Natesan, Abuzenadah, Adel, Al-Qahtani, Mohammed Hussein
Formato: Artigo
Idioma:Inglês
Publicado em: Biomedical Informatics 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599435/
https://ncbi.nlm.nih.gov/pubmed/31285644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630015269
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