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Single cell RNA-Seq reveals pre-cDCs fate determined by transcription factor combinatorial dose

BACKGROUND: Classic dendritic cells (cDCs) play a central role in the immune system by processing and presenting antigens to activate T cells, and consist of two major subsets: CD141(+) cDC (cDC1) and CD1c(+) cDC (cDC2). A population of migratory precursor cells, the pre-cDCs, is the immediate precu...

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Podrobná bibliografie
Vydáno v:BMC Mol Cell Biol
Hlavní autoři: Ma, Wenji, Lee, Jaeyop, Backenroth, Daniel, Zhou, Yu Jerry, Bush, Erin, Sims, Peter, Liu, Kang, Shen, Yufeng
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599345/
https://ncbi.nlm.nih.gov/pubmed/31253076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-019-0199-y
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