Evaluation of systemic absorption and bronchodilator effect of glycopyrronium bromide delivered by nebulizer or a dry powder inhaler in subjects with chronic obstructive pulmonary disease

BACKGROUND: Effective bronchodilator therapy depends upon adequate drug deposition in the lung. COPD patients who are unable to administer medications efficiently with conventional inhalers may benefit from the use of a nebulizer device. The aim of this study was to evaluate the systemic bioavailabi...

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Dades bibliogràfiques
Publicat a:Respir Res
Autors principals: Leaker, Brian R., Singh, Dave, Nicholson, Grant C., Hezelova, Blanka, Goodin, Thomas, Ozol-Godfrey, Ayca, Galluppi, Gerald, Barnes, Peter J.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599298/
https://ncbi.nlm.nih.gov/pubmed/31253162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-019-1113-z
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