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Dual pathways of tRNA hydroxylation ensure efficient translation by expanding decoding capability

In bacterial tRNAs, 5-carboxymethoxyuridine (cmo(5)U) and its derivatives at the first position of the anticodon facilitate non-Watson–Crick base pairing with guanosine and pyrimidines at the third positions of codons, thereby expanding decoding capabilities. However, their biogenesis and physiologi...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Sakai, Yusuke, Kimura, Satoshi, Suzuki, Tsutomu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599085/
https://ncbi.nlm.nih.gov/pubmed/31253794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10750-8
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