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Polyhistidine facilitates direct membrane translocation of cell-penetrating peptides into cells

The bovine lactoferricin L6 (RRWQWR) has been previously identified as a novel cell-penetrating peptide (CPP) that is able to efficiently internalize into human cells. L6 interacts with quantum dots (QDs) noncovalently to generate stable L6/QD complexes that enter cells by endocytosis. In this study...

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Publicat a:Sci Rep
Autors principals: Lee, Han-Jung, Huang, Yue-Wern, Chiou, Shiow-Her, Aronstam, Robert S.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599048/
https://ncbi.nlm.nih.gov/pubmed/31253836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45830-8
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