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Conserved transcriptomic profile between mouse and human colitis allows unsupervised patient stratification

Clinical manifestations and response to therapies in ulcerative colitis (UC) are heterogeneous, yet patient classification criteria for tailored therapies are currently lacking. Here, we present an unsupervised molecular classification of UC patients, concordant with response to therapy in independe...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Czarnewski, Paulo, Parigi, Sara M., Sorini, Chiara, Diaz, Oscar E., Das, Srustidhar, Gagliani, Nicola, Villablanca, Eduardo J.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6598981/
https://ncbi.nlm.nih.gov/pubmed/31253778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10769-x
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