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Conserved transcriptomic profile between mouse and human colitis allows unsupervised patient stratification

Clinical manifestations and response to therapies in ulcerative colitis (UC) are heterogeneous, yet patient classification criteria for tailored therapies are currently lacking. Here, we present an unsupervised molecular classification of UC patients, concordant with response to therapy in independe...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Czarnewski, Paulo, Parigi, Sara M., Sorini, Chiara, Diaz, Oscar E., Das, Srustidhar, Gagliani, Nicola, Villablanca, Eduardo J.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6598981/
https://ncbi.nlm.nih.gov/pubmed/31253778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10769-x
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