Immunization With Mycobacterium tuberculosis Antigens Encapsulated in Phosphatidylserine Liposomes Improves Protection Afforded by BCG

Liposomes have been long considered as a vaccine delivery system but this technology remains to be fully utilized. Here, we describe a novel liposome-based subunit vaccine formulation for tuberculosis (TB) based on phosphatidylserine encapsulating two prominent TB antigens, Ag85B, and ESAT-6. We sho...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Diogo, Gil R., Hart, Peter, Copland, Alastair, Kim, Mi-Young, Tran, Andy C., Poerio, Noemi, Singh, Mahavir, Paul, Matthew J., Fraziano, Maurizio, Reljic, Rajko
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6598733/
https://ncbi.nlm.nih.gov/pubmed/31293568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01349
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