Exploratory analyses of consensus molecular subtype-dependent associations of TP53 mutations with immunomodulation and prognosis in colorectal cancer

BACKGROUND: Accumulating evidence suggests immunomodulatory and context-dependent effects of TP53 mutations in cancer. We performed an exploratory analysis of the transcriptional, immunobiological and prognostic associations of TP53 mutations within the gene expression-based consensus molecular subt...

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Detalhes bibliográficos
Publicado no:ESMO Open
Main Authors: Smeby, Jørgen, Sveen, Anita, Bergsland, Christian H, Eilertsen, Ina A, Danielsen, Stine A, Eide, Peter W, Hektoen, Merete, Guren, Marianne G, Nesbakken, Arild, Bruun, Jarle, Lothe, Ragnhild A
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6598553/
https://ncbi.nlm.nih.gov/pubmed/31321083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/esmoopen-2019-000523
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