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Spatially Defined Drug Targeting by in Situ Host–Guest Chemistry in a Living Animal

[Image: see text] Ensuring effective drug concentration specifically at sites of need, while limiting systemic side effects, remains a challenge in the discovery and use of new drug molecules. Carriers targeted through biological affinity (e.g., antibodies) afford a common means of drug localization...

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Détails bibliographiques
Publié dans:ACS Cent Sci
Auteurs principaux: Zou, Lei, Braegelman, Adam S., Webber, Matthew J.
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2019
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6598162/
https://ncbi.nlm.nih.gov/pubmed/31263763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.9b00195
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